By Wolfgang Beermann (auth.), W. Beermann (eds.)
Earlier titles during this sequence have directed awareness to chose questions of present theoretical or functional curiosity in developmental biology, with out exact emphasis upon person organic structures. Tho opt for gigantic polytene chromosomes because the universal denominator of a brand new quantity might initially sight appear to set really arbitrary regulations upon a coherent dialogue of the elemental challenge of mobile differentiation. even if, the reader will discover for hirnself that, to the contrary, the sort of problem, although dicta ted via the fabric, focuses the research upon one crucial aspect: the differential unencumber of genetic info from operational subunits of the eukaryotic chromosome. within the association of this quantity we've not striven for completeness - a few, certainly, might price 1 that the paintings on Sciarids is underrepresented - however the quite a few participants have made each attempt to render a radical and up to date photo of the location of their specific box, and in this foundation to debate all attainable angles of basic organic curiosity. Authors and editors have agreed to devote this quantity to the reminiscence of JACK SCHULTZ.
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Lampbrush chromosomes of crested newts Triturus cristatus (Laurenti). Phil. Trans. Roy. Soc. London, B 243, 135~219 (1960). : Les chromosomes salivaires polytcnes chez Bilobella grassii. ) 35, 57~83 (1971). CRICK, F. : General Model for the Chromosomes of Higher Organisms. ) 234, 25~27 (1971). : Extra replications in the "DNA-puffs" of Sciara coprophila. ) 25, 357~364 (1968). : The nature of changes in the white-Notch region of the X chromosome of Drosophila melanogaster. Proc. 7th Int. Genet.
A fully evolved chromomere would thus have only one "sensible" gene at its beginning, this initial segment being followed by an appendix of nonsense DNA sequences which, although being transcribed, possess only auxiliary functions. In summarizing this discussion, the following view of the eukaryotic genome emerges: The basic structural and functional unit of the eukaryotic chromosome is the chromomere, or the chromomere-interchromomere complex. As a rule only one pro tein co ding sequence, or cistron, seems to exist within each chromomere-interchromomere complex.
Cell Res. 6, 195~201 (1954). BERENoEs, H. : Polytene chromosome structure at the submicroscopic level: 1. A map of region X, 1~4E of Drosophila melanogaster. ) 29, 118~130 (1970). BRIDGES, C. : Salivary chromosome maps. J. Heredity 26, 60~64 (1935). ~ A revised map of the sali vary gland X chromosome of Drosophila melanogaster. J. Heredity 29, 11~13 (1938). BRITTEN, R. , DAVIDSON, E. : Gene regulation for higher cells: A theory. Science 165, 349~357 (1969). CALLAN, H. : The organization of genetic units in chromosomes.