By Gordon Guyatt, Drummond Rennie, Maureen Meade, Deborah Cook

The streamlined spouse to the vintage Users' courses to the clinical Literature--fully up to date and revised

This compact consultant condenses the main clinically appropriate content material of the landmark Users' publications to the scientific Literature that will help you contain evidence-based drugs into your practice.

You will study the rules of evidence-based medication, how your perform can enjoy the consistent movement of recent scientific literature, and the way to distinguish stable clinical proof from that that's insufficient or misleading.

This version contains a variety of updates, numerous new chapters, and a better emphasis at the position of sufferer personal tastes and preappraised resources.

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Additional info for Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice, Third Edition

Example text

11 Best Evidence Summaries In 1992, Antman et al2 published an article that compared the recommendations of experts for management of patients with myocardial infarction to the evidence that was available at the time the recommendations were made. Figures 2-1 and 2-2 summarize their results in forest plots. Both are cumulative meta-analyses: the first of thrombolytic therapy for myocardial infarction and the second for lidocaine antiarrhythmic therapy. 0 (treatment is neither beneficial nor harmful).

Html). If your specialty does not yet have its own journal, you can apply your own relevance and methodologic screening criteria to articles in your target specialty or subspecialty journals. When you have learned the skills, you will be surprised at the small proportion of studies to which you need attend and the efficiency with which you can identify them. ” Here, clinicians are defining specific 3: What Is the Question? 29 questions raised in caring for patients and then consulting the literature to resolve these questions.

Figure 3-6 Structure of Studies of Diagnostic Test Properties Target condition present Patients suspected of having target condition Diagnostic test Gold standard test Target condition absent Figure 3-7 Structure of Studies of Prognosis Experience target outcome Patients at risk of experiencing target event Prognostic factor Time Do not experience target outcome 3: What Is the Question? 35 Three Examples of Question Clarification We will now provide examples of the transformation of unstructured clinical questions into the structured questions that ­facilitate the use of the medical literature.

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