By Martine Extermann MD, Lodovico Balducci, William B. Ershler, Gary H. Lyman, Martine Extermann

The prevention and remedy of melanoma in older sufferers calls for an individualized technique, as age motives unpredictable effects from sufferer to sufferer. thoroughly revised and up-to-date, this moment version of a bestseller permits clinicians to settle on the very best melanoma care. Highlighting rising concerns in geriatric oncology, it is helping physicians advertise melanoma prevention and exhaustively reports the biology of melanoma and getting older, epidemiologic traits, and scientific trials. New chapters comprise fabric on themes equivalent to review, fragility, symptom administration, and emergencies, and stories of the effectiveness of teaching courses in geriatric oncology.

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The values of two variables may be varied simultaneously, generating a threshold function. Obviously, any combination of values of the two variables that do not lie on the threshold curve will result in expected values favoring one strategy or the other. Likewise, the values of three variables may be varied simultaneously, yielding a family of threshold curves. In theory, any number of variables may be varied simultaneously, although such an analysis is limited by the ability to conceptualize and graphically depict such relationships.

24. Rosenberg SA. Non-Hodgkin’s lymphoma—selection of treatment on the basis of histologic type. N Engl J Med 1979; 301:924–8. 25. Lichtman SM. Lymphoma in the older patient. Semin Oncol 1995; 22(Suppl 1): 25–8. 26. Hosking MP, Warner MA, Lobdell CM et al. Outcomes of surgery in patients 90 years of age and older. JAMA 1989; 261:1909–15. 27. Trimble EL, Carter CL, Cain D et al. Representation of older patients in cancer treatment trials. Cancer 1994; 74:2209–14. 28. Hutchins LF, Unger JM, Crowley JJ et al.

In the next several decades, geriatric and cancer care will become a significant medical, public health, economic, and social challenge. 29 It was perceived that cancer in the aging population would be a major health problem. The number of certified medical oncologists has grown at an awesome rate since 1973, and is now well over 8100. Yet a surplus of medical oncologists is not anticipated. The need for oncology manpower will surpass that for cardiology. 30,31 It is reasonable to assume that primary care physicians will be more responsible for teaching cancer prevention, emphasizing early cancer detection, and administering some of the standard therapies.

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