By Donald A. Molony M.D., Jonathan C. Craig
This e-book covers the administration of all significant renal illnesses from an evidence-based and patient-centred method. With contributions from major foreign specialists who've a true figuring out of evidence-based medication it presents tips about therapy regimens to undertake for person sufferers which are such a lot strongly supported through the evidence.
The inclusion of the most recent observational and epidemiological facts, in addition to randomized managed trial facts guarantees that the publication safely displays the present nation of facts on hand for nephrological perform. will probably be an invaluable reduction to all clinicians, together with these taking good care of transplant and pediatric sufferers, because it covers the key scientific questions encountered through nephrologists.
This reference is a useful resource of evidence-based info distilled into advice for medical perform so that it will be welcomed through practitioners, trainees and linked health and wellbeing professionals.
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Additional info for Evidence-Based Nephrology (Evidence-Based Medicine)
Example text
This has been documented by the finding that the mortality risk for wait-listed transplant candidates on dialysis is substantially lower than for all dialysis patients who are not (yet) wait-listed [85]. e. comorbidities and demographics). This can be accomplished in part through statistical adjustment for those factors that are recorded. The DOPPS and other studies showed that a long list of factors needs to be considered to allow meaningful comparisons between treatments, Chapter 1 Epidemiology of Chronic Kidney Disease patient groups, regions, or centers.
7), stage 2 CKD was noted in 41% of KEEP participants, with a range of 39–42% among different race and ethnic groups. Stage 3 CKD was found in 42% of the White population compared with 17–21% in other racial and ethnic groups [31]. 60 50 Percent with CKD KEEP NHANES 40 30 20 10 0 All CKD Stage 1 Stage 2 Stage 3 Province of British Columbia The British Columbia Renal Agency (BCPRA) and the British Columbia Ministry of Health Services have jointly developed a patient register to help identify and track the quality of care and status of patients at all stages of CKD, including at-risk populations.
Survival after initiation of RRT Morbidity and mortality are high in late stages of CKD and remain high among those who survive to the start of dialysis therapy. After initiation of dialysis, mortality depends largely on patient characteristics and comorbid conditions, particularly age and diabetes. Comparative studies of treatment modalities have clearly identified that kidney transplantation provides superior outcomes [85], and even more so when from a living donor [86]. Studies of the mortality risk for peritoneal dialysis versus hemodialysis have been somewhat inconclusive, as no large randomized studies of these dialytic treatment options have been performed and patient selection may influence the outcomes.