By Charles Wiener
Add the unequalled authority of Harrison’s for your board assessment or attempt preparation
1,100 overview questions!
Based at the content material of Harrison’s rules of inner medication, 18e, this robust examine instrument is vital for inner medication Board certification or recertification/maintenance of certification, or as a refresher for any inner medication examination.
Reflecting the accuracy and timeliness of Harrison’s, this entire overview of inner medication positive factors greater than 1,100 evaluate questions, lots of which make the most of sensible sufferer situations, together with radiographic or pathologic pictures. each one query is observed via a whole solution and rationalization derived from – and cross-referenced to – Harrison’s rules of inner medication, 18e. those questions are designed to reinforce your realizing of pathophysiology, epidemiology, differential analysis, scientific choice making, and therapeutics.
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- content material that heavily follows the association and assurance of the 18th version of Harrison’s rules of inner Medicine
- greater than 1,100 Q&As that simulate these at the basic certification exam in inner drugs
- unique solutions causes for every query
- assurance that spans the whole spectrum of inner drugs
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- every one subject is roofed in share to its point of significance at the inner drugs exam Blueprint
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5) Some medications circulate in the plasma partially bound to plasma proteins. In this setting, only unbound (or free) drug can distribute to the sites of action to exert pharmacologic effects. Examples of medications that are bound to plasma proteins include phenytoin, warfarin, valproic acid, and amiodarone. Hypoalbuminemia can lead to increased free levels of drugs that are more highly protein bound and can lead to drug toxicity at total drug levels that are not typically considered toxic. In this case, the patient has evidence of worsening liver disease with a low albumin level that has lead to signs and symptoms of phenytoin toxicity.
It begins in the first 24 hours after treatment and is associated with fevers, myalgias, headaches, and tachycardia. Disseminated gonococcal infection presents as an asymmetric migratory polyarthritis with fever and a papular or pustular rash. Septic arthritis may occur. A negative urethral swab result does not rule out this possibility, but the clinical presentation is not consistent with disseminated gonococcal infection. Approximately 10–20% of patients with rheumatoid arthritis have a negative rheumatoid factor.
The answer is E. (Chap. 2) The causes of morbidity and burden of disease in a population differ from the absolute causes of mortality in a population. 0 million disability-adjusted life years lost (DALYs) in high-income countries. Depression is quite common in the general population of developed countries. However, the death rate from depression is low and is mainly reflected in suicides. Thus, depression creates disability and lost productivity without a significant impact on years of life lost.