By Medha N. Munshi, Lewis A. Lipsitz

The variety of aged sufferers with diabetes is expanding at an important fee. Responding to this development, this resource serves as a pretty good arsenal of knowledge at the various displays and demanding situations linked to diabetes within the geriatric sufferer, and provides basically written sections at the screening, analysis, and remedy of diabetes in aged populations. With contributions from popular experts from the nationwide and foreign associations, this reference will depict the position of particular co-morbidities, socioeconomic points, and caregiver concerns at the powerful administration of diabetes within the older grownup.

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Mol Genet Metab 2000; 70(2): 151–158. 149. Hansen L, Hansen T, Vestergaard H, et al. A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin. Hum Mol Genet 1995; 4(8):1313–1320. 150. Xia J, Scherer SW, Cohen PT, et al. A common variant in PPP1R3 associated with insulin resistance and type 2 diabetes. Diabetes 1998; 47(9):1519–1524. 151. Maegawa H, Shi K, Hidaka H, et al.

Rasmussen SK, Urhammer SA, Berglund L, et al. Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians. Diabetes 2002; 51(12):3561–3567. 41. Fingerlin TE, Erdos MR, Watanabe RM, et al. Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort. Diabetes 2002; 51(5):1644–1648. 42. Elbein SC, Chu W, Ren Q, et al.

The vitamin D receptor polymorphism in the translation initiation codon is a risk factor for insulin resistance in glucose tolerant Caucasians. BMC Med Genet 2001; 2:2. 165. Walston J, McBurnie MA, Newman A, et al. Frailty and activation of the inflammation and coagulation systems with and without clinical morbidities: results from the cardiovascular health study. Arch Intern Med 2002; 162:2333–2341. 166. Maggio M, Guralnik JM, Longo DL, Ferrucci L. Interleukin-6 in aging and chronic disease: a magnificent pathway.

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