By Fernando C. Fervenza, James Pattison, David Goldsmith, Joseph P. Grande, Barrie Hartley
A convenient sized reference quantity for physicians in perform and coaching: prognosis, research, management;chapter order displays the 'stages' of renal ailment as obvious in patients;one consistent with web page or unfold of pages;superb color illustrations built-in all through - combining the benefits of an atlas with a quick text/reference.
summary:
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Additional info for Renal Medicine : a Colour Handbook
Example text
G. g. g. g. colon cancer, lung cancer). In patients over the age of 60 years, membranous nephropathy is associated with a malignancy in 7–15% of patients. INVESTIGATIONS Similarly to other patients with nephrotic syndrome, hyperlipidemia is common. Renal impairment may be present. Lowered serum complement levels may suggest a diagnosis of SLE. Hepatitis B and C serology should be performed. HISTOLOGY Very early on in the disease process the glomeruli may be normal on light microscopy, and the diagnosis can be made only by immunofluorescence or electron microscopy.
Connective tissue diseases, metastatic cancer, lymphoma, or leukemia may share some clinical features with myeloma. Multiple myeloma also needs to be distinguished from monoclonal gammopathy of uncertain significance, smouldering multiple myeloma, and primary amyloidosis. INVESTIGATIONS A standard myeloma workup includes a full blood count, serum creatinine and calcium, serum electrophoresis and paraprotein quantification, a 24-hour urine collection for electrophoresis and immunofixation, a bone marrow examination, and a skeletal survey (58).
The use of immunosuppression in the setting of idiopathic membranous glomerulopathy is controversial, especially because of the variable natural history of the disease and of drug toxicity. Immunosuppression is generally reserved for those patients with deteriorating renal function and/or heavy proteinuria. Various agents have been used including corticosteroids, cytotoxics such as cyclophosphamide, chlorambucil, and azathioprine or cyclosporine (cyclosporin). 2 mg/kg daily for 1 month. This cycle was repeated until 6 months’ treatment had been given.