By Dr. S. van Houten (auth.)
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Extra info for The Way Out
Die Mutterkornalkaloide. Stuttgart: Ferdinand Enke Verlag, 1964. Reprinted Solothurn, Switzerland: Nachtschatten Verlag, 2000. indd 35 3/28/13 4:11 PM 36 Planning and Chance in Pharmaceutical and Chemical Research Franz Troxler. ” Helvetica Chimica Acta 42 (1959): 1557–72. Hofmann’s article about the Mexican magic mushroom (Psilocybe mexicana) research. indd 37 3/28/13 4:11 PM If a chemist does not become a mystic, then he is not a chemist either. indd 38 3/28/13 4:11 PM 2 Can Insight into the Truths of Natural Science Be Therapeutically Effective in Psychology?
A. Jacobs and L. C. indd 16 3/28/13 4:11 PM 17 Planning and Chance in Pharmaceutical and Chemical Research named lysergic acid. They demonstrated that lysergic acid and the amino alcohol L-2-aminopropanol could be obtained through an alkaline hydrolysis of ergobasine. A complex structure was ascertained for ergotamine and ergotoxine, which showed how lysergic acid binds with a tripeptide-type residue. At this time I had just finished my first substantial work at the Stoll laboratory: the structural elucidation of the Scilla glycoside.
This unusual state of consciousness, which was not unpleasant, vanished after a few hours. I suspected that I had been intoxicated by something in my laboratory. At first I thought the cause might be the dichloroethylene that I had used in the chromatography. The next day at work I cautiously inhaled some vapor from this solvent. But nothing happened. Then I tested the lysergic acid diethylamide that I had also worked with on the day of the incident. But because I had been habitually working in a clean environment with the ergot alkaloids I could not actually imagine how I could have possibly taken enough of this substance for it to have any effect.