By Eliane Schutte

Written via a world team of specialists, regulators, and teachers, this new ASTM book offers the newest facts on tissue engineering and the criteria on hand for production TEMPs. Twenty-three peer-reviewed papers conceal: • present know-how • latest criteria • improvement of latest criteria • overseas criteria utilized by Regulatory our bodies This new book serves as a invaluable source for regulators, brands, providers, builders, teachers, patent examiners, and legal professionals.

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Extra resources for Tissue Engineered Medical Products (TEMPs) ASTM special technical publication, 1452

Sample text

Raw, G, and H values are summarized in Table I. In both groups, BLVR was associated with normalization of physiological parameters to pre-emphysema baseline values at the BVRo2 follow-up time points. Table 1-- Summary of dynamic lungfunction. 7• Diffusing capacity To evaluate the effectiveness of gas exchange at the alveolar level, diffusing capacity was measured in both groups of animals. Results show that papain exposure caused significant reductions in diffusing capacity, which improved following BLVR treatment (Figure 4).

112: pp. 1319-1330. 14. " Chest, 1999. 116(6): pp. 1608-15. 15. D. S. Lefrak, "Lung-reduction surgery: 5 years on. "Lancet, 1999. 353(Suppl 1): pp. 26-27. 16. , "Interpreting improvement in expiratory flows after lung volume reduction surgery in terms of flow limitation theory. "Am JRespir Crit Care Med, 2001. 163(5): pp. 1074-80. 17. , "No-cut thoracoscopic lung plication: a new technique for lung volume reduction surgery. "JAm Coll Surg, 1997. 185(1): pp. 25-32. 18. , "Limitations of randomized clinical trials for evaluating emerging operations: the case of lung volume reduction surgery.

Neither thrombin nor fibrinogen is intended to exert a direct pharmacological effect, however. The primary function of the hydrogel is to provide a scaffold that immobilizes INGENITO ET AL. ON BRONCHOSCOPIC LUNG VOL. REDUCTION components needed to initiate a localized biological response that leads to volume reduction through scar formation and contraction. The hydrogel contains two active components that promote localized scar formation in the absence of inflammation. These are: 1. Chondroitin-6-sulfate (CS), a naturally occurring glyeosaminoglycanused in tissue engineering applications to foster skin and nerve regeneration [23-25]; 2.

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