By Kazumasa Kurosumi (auth.), P. M. Motta M.D., Ph.D. (eds.)

Innovative microscopic concepts, brought over the past 20 years, have contributed a lot to making a brand new photo of the dynamic structure of the telephone, that may now be extra precisely correlated with particular biochemical and physiopathological occasions. those advancements have resulted in major advances in our knowing of the physiomorphological and pathological facets of the secretory mechanism, in addition to the pharmacologic equipment used to manage, experimentally, the functionality of exocrine and endocrine glands. the mixing of recent ultrastructural tools corresponding to freeze-fracture/etching, immunocytochemistry, scanning and high-voltage electron microscopy, cytoautoradiography, and so on. , has confirmed to be of serious worth while utilized to the research of endocrine cells and tissues. simply because info in this subject has seemed in numerous clinical and clinical journals, this publication: (1) reports the result of an integrative strategy offering a entire ultrastructural account of the most facets of the sphere; (2) issues out gaps or arguable issues in our wisdom; and (3) outlines pertinent instructions for destiny examine. The chapters, ready via well-known specialists within the box, current conventional info at the subject in a concise demeanour and, with a worthwhile choice of unique illustrations, convey what the combination of recent microscopic equipment can give a contribution to the topic by way of new ideas. This quantity may be helpful to phone biologists, anatomists, embryologists, histologists, pharmacologists, pathologists, and, in fact, endocrinologists. it's going to even be of curiosity to scholars, practitioners of drugs, and to all others facing medical examine and diagnosis.

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In most species, the majority of glandular cells belong to a cell type peculiar to the PT and these cells are not found in other adenohypophysial lobes and are therefore called 'specific PT cells'. In the rodent PT, they are the sole glandular cell type present in the cephalic zone of the PT. Different quantities of PD cell types, mainly gonadotrophs, are found in the caudal PT of various mammals. 1. 1. Specific glandular cells Viewed with the electron microscope, these cells show characteristic features of peptide-secreting cells.

Z Zellforsch 136(2): 207-214, 1973. 109. Ishimura K, Egawa K, Fujita H: Freeze-fracture images ofexocytosis and endocytosis in anterior pituitary cells of rabbits and mice. Cell Tissue Res 206(2): 233-241, 1980. Author's address: Department of Histology-Embryology-Cytogenetics Faculte de Medecine Alexis Carrel Rue Guillaume Paradin F - 69372 Lyon Cedex 2 (France) CHAPTER 3 Fine structure and development of the pars tuberalis in mammals MARIE-ELISABETH STOECKEL and AIME PORTE 1. Introduction The precise function of the tuberal lobe or pars tuberalis (PT) of the adenohypophysis identified anatomically by Tilney (1) and embryologically by Atwell (2) still poses an enigma (3).

Ann Sci natur, Zool 15(12e serie): 61-138,1973. 18. Farquhar MG, Skutelsky EH, Hopkins CR: Structure and function of the anterior pituitary and dispersed pituitary cells in vitro studies. In: The anterior pituitary. Tixier-Vidal A, Farquhar MG(eds), New York-San Francisco-London, Academic Press, 1975, pp 83-135. 19. Kurosumi K: Adenohypophysis. In: Functional morphology of endocrine glands. Kurosumi K, Fujita H (eds), Stuttgart-Tokyo, G Thieme-Igaku Shoin Ltd, 1975, pp 1-100. 20. Pantie VR: The specificity of pituitary cells and regulation of their activities.

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