By Lester J. Layfield, Jonathan S. Berek (auth.), Mace L. Rothenberg (eds.)

More usually than no longer, development in medication happens incrementally. The record of an 'important' new statement is sometimes greeted through a mix of pleasure and skepticism. but the real price of the invention is probably not identified for a number of years until eventually it's proven (or refuted) by means of independently carried out experiences. every now and then, controversy might proceed to shroud a subject as a result of the discordant effects generated via assorted study teams. because the final Gynecologic Oncology quantity within the melanoma remedy and examine sequence, a few new components have emerged that shed new gentle at the pathogenesis, prognosis, and therapy of gynecologic malignancies. during this quantity of the melanoma therapy and study sequence, i've got tried to combine articles that spotlight a few of these most modern advancements with chapters that offer an outline of chosen components of controversy. This quantity isn't intended to be an abbreviated textual content of gynecologic oncology yet quite a set of chosen works that could give you the reader with a greater standpoint at the components of swap in the box. the applying of molecular biology to cervical melanoma has allowed us to appreciate extra thoroughly the jobs of human papilloma viruses and mobile oncogenes within the improvement of melanoma of the uterine cervix.

Show description

Read or Download Gynecologic Oncology: Controversies and New Developments PDF

Best nonfiction_10 books

New Trends and Developments in Vaccines

It used to be recently that many physicians and biomedical scientists felt that the period of 'vaccines' for safeguarding mankind opposed to infectious sickness used to be coming to an finish. in the course of the 1 940s and 50s the frequent use of newly built antibiotics and antimicrobial chemotherapeutic brokers steered a brand new period in medication, i.

Analytical Graphite Furnace Atomic Absorption Spectrometry: A Laboratory Guide

"One should still quite cross horne and mesh a internet than leap into the pond and dive a ways fishes" (Chinese proverb) spotting the best analytical query and making plans the research in accordance­ ly is unquestionably the 1st prerequisite for profitable hint and ultratrace determina­ tions. the second one prerequisite is to pick the tactic acceptable to the analyti­ cal specification.

Extra info for Gynecologic Oncology: Controversies and New Developments

Example text

21. Morin C, Braun L, Casas Cordero M, Shah K, Roy M, Fortier M, Meisels A (1981). Confirmation of the papillomavirus etiology of condylomatous cervix lesions by the peroxidase anti-peroxidase technique. J Natl Cancer Inst 66:831-835. 22. Kurman RJ, Jenson AB, Lancaster WD (1983). Papillomavirus infection of the cervix II. Relationship to intraepithelial neoplasia based on the presence of specific viral structural proteins. Am J Surg Pathol 7:39-40. 23. Gissmann L, Villiers EM, zur Hausen H (1980).

The committee's rationale for inclusion of pure HPV with lowgrade SIL relates to the strongly suspect relationship of HPV and cervical carcinogenesis as well as the similar progression rate to high-grade lesions of pure HPV (flat condyloma - 14%) and CIN 1 (16%) [33,34]. It has been argued that the reproducibility of the three-tier CIN system is poor [35,36], and that therefore the traditional CIN grading does not really provide additional information. Furthermore, since CIN 2 and 3 should be treated in the same way, identification of the lesion as high-grade is most important for patient management [37].

Int J Gynecol Pathol 10:326-328. 42. Soloway HB, Belliveau RR (1991). The Bethesda classification system: A counterintuitive approach to data presentation. Hum Pathol 22:401-402. 43. Anderson G (1991). Bethesda System of reporting: A Canandian viewpoint. Diagn Cytopathol 7:559-561. 44. Hudson EA, Coleman DV, Brown CL (1990). The 1988 Bethesda System for reporting cervical/vaginal cytologic diagnoses. Acta Cytol 34:907-903. 45. Hudson EA (1990). Cytological terminology. Br J Obstet GynecoI97:202-204.

Download PDF sample

Rated 4.12 of 5 – based on 48 votes