By Marc E. Agronin MD, Gabe J. Maletta PhD MD
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Additional resources for Principles and practice of geriatric psychiatry
Decrease in optimal central nervous system executive function together with these changes results in a decline in older persons to perform two tasks at once— dual tasking. IMMUNE SYSTEM Psychoneuroimmunology principles have stressed the important interactions between the brain and the immune system. Additionally, increased peripheral cytokine production is a major cause of delirium, and older persons have an increase in interleukin-6 production. 3/29/2011 10:31:49 AM Chapter 1: The Aging Body and Brain With aging, there is a decrease in cell-mediated antibody production and increased production oflower affinity antibodies and of antiidiotype antibodies.
Seventy-two percent of older Americans reported their health as good, very good, or excellent. Women and men reported comparable levels of health status ( 1). Positive health evaluations decline with age. Among nonHispanic White men aged 65 to 74, 76% reported good-toexcellent health, compared with 67% ofnon-HispanicWhite men 85 or older. A similar decline with age was reported by non-Hispanic Black and Hispanic older men, and by women, with the exception of non-Hispanic Black women. Among older men and women in every age group, nonHispanic Black and Hispanic people were less likely to report good health than non-Hispanic White people.
Age and sex differences in reaction time in adulthood: results from the United Kingdom health and lifestyle survey. Psychol Aging. 2006;21:62–73. 15. Wilson RS, Beckett LA, Bennett DA, et al. Change in cognitive function in older persons from a community population: relation to age and Alzheimer disease. Arch Neurol. 1999;56:1274– 1279. 16. Zacks RT, Hasher L, Li KZH. Human memory. In: Craik FI, Salthouse TA, eds. The Handbook of Aging and Cognition, 2nd ed. Mahwah, NJ: Lawrence Erlbaum Associates, 2000.