By Vincenzo Cambi (auth.), Vincenzo Cambi M.D. (eds.)

Vittorio E. Andreucci of preserving alive sufferers in terminal continual first and foremost created with the aim renal failure, dialysis has gone through advancements in method, and its ultimate aim has turn into entire future health rehabilitation and optimization of the standard of lifetime of power dialysis sufferers. to accomplish this, many investigators have tried to extend dialysis potency and even as shorten dialysis time. Their major obstacle was once, evidently, sufferer safeguard: the Latin proverb 'primum non nocere' continues to be legitimate worldwide. therefore, whilst scientific observations of the 1st sufferers on commonplace dialysis remedy recommended an inverse courting among length of dialysis classes and severity of peripheral neuropathy, lengthy and common dialysis classes have been thought of the single solution to hinder the catastrophic outcomes of nerve harm and underdialysis syndrome. It used to be then, in 1971, whilst dialysis length used to be eight- 12 hours in step with consultation, that Vincenzo Cambi began a 'short dialysis' trial, i. e. , four hours three times weekly or three hours each moment day. For the 1st time, dialysis was once shortened from 24-36 hours weekly to ten. 5-12 hours weekly [1, 2]. In 1971 i used to be nonetheless on the Parma collage health facility. We had either simply again from the us, and Dr. Cambi was once chargeable for the dia­ lysis unit.

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11. M. (1974) Clinical Evaluation of patients dialysed with double gambro 4 hours, three times per week. Proc. Eur. Dial. Transpl. Ass. 11: 121. 12. , Koshikawa, S. and Yamada, T. (1978) comparison of dialysis programmed on different molecular prescriptions: a preliminary study. Proc. Europ. Dial. Transp. Ass. 14: 167. 13. , Ramperez, P. and Mion, C. (1978) The importance of serum osmotic changes in symptomatic hypotension during short dialysis. Proc. Clin. Dial. Transpl. Forum 8: 35. 14. , Foster, R.

H. (1965) Discussion. Trans. Amer. Soc. Artif. Int. organs 11: 29. 3. Shaldon, S. (1966) Haemodialysis in chronic renal failure. Post Graduate Medical Journal (Supplement) 12/680. Kent: Kent Arms Printing Works Ltd. 4. G. H. (1971) The genesis of the square meter-hour hypothesis. Trans. Am. Soc. Art. Int. org. 17: 91. 5. L. H. (1971) A study of haemodialysis with lowered dialysate flow rate. Proc. Am. Soc. Art. Int. Org. 17: 92. 6. A. E. (1971) Assay of serum abnormalities in uremic and dialysis patients.

Zo 20 15 10 5 74 75 76 77 78 79 80 81 82 83 84 YEARS IIEnfEEII 1974 - 1984 Figure 2-3. Curve indicating survival of patients who entered short dialysis in 1974. 5%. Thirty-five patients began short dialysis; 20 were alive as of December 31, 1984. 9 months. Five patients underwent PTX, two underwent pericardiotomy for dialysis paricarditis. Eight patients were hypertensive before starting treatment and afterwards became normotensive or hypotensive; 5 patients who were hypertensive before treatment remained hypertensive; the other 7, who had normal BP values before treatment, tend, at present, to be hypotensive.

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